Qualificação de doutorado do discente Lauro Moraes; Terça-feira, 15 de outubro as 13:30·

Qualificação de doutorado do discente Lauro Moraes; Terça-feira, 15 de outubro as 13:30·

Título: Identification of Promoter Regions in DNA with Capsules

Resumo:

With the advent of new DNA sequencing technologies, there is a wealth of information that needs to be processed and analyzed effectively. Consequently, new studies are focusing on the introduction of novel techniques for handling fundamental tasks in the field of bioinformatics. A critical task is functional genomic annotation, which requires accurate identification of promoter regions. These regions play crucial regulatory roles in gene transcription. Despite several methodologies proposed in the literature to identify these regions, it remains an unresolved problem. Some research has been conducted using various artificial neural network architectures. In this text, we present fundamental concepts for the identification of promoter regions in DNA sequences using machine learning techniques. We have performed experiments using various machine learning models and examined the performance of capsule-based networks. Furthermore, we discuss and present our two published articles, derived from our studies in this project and their contributions. The first article introduces an approach based on capsule neural networks, while the second explores using physicochemical properties as attributes for machine learning models. We conclude the text with a brief final discussion and outline the schedule of the upcoming activities for this project.

Link da videochamada: https://meet.google.com/joz-kjih-ydz

Membros da banca: Prof. Dr. Gladston Juliano Prates Moreira (Orientador - UFOP); Prof. Dr. Eduardo José da Silva Luz (Coorientador - UFOP); Prof. Dr. Jadson Castro Gertrudes (UFOP); Prof. Dr. João Carlos Setubal (USP); Profa. Dra. Joicymara Santos Xavier (UFVJM)